ENTERIC MRI CONTRAST AGENTS - COMPARATIVE-STUDY OF 5 POTENTIAL AGENTS IN HUMANS

被引：20

作者：

TART, RP

LI, KCP

STORM, BL

ROLFES, RJ

ANG, PGP

机构：

[1] Department of Radiology, University of Florida College of Medicine, Gainesville

来源：

MAGNETIC RESONANCE IMAGING | 1991年 / 9卷 / 04期

关键词：

CONTRAST AGENTS; GASTROINTESTINAL; GRADIENT ECHO; MAGNETIC RESONANCE; OIL EMULSION;

D O I：

10.1016/0730-725X(91)90043-L

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

We compared the effectiveness of 1 mM Geritol, 12% corn oil emulsion, Kaolin-pectin, single contrast oral barium sulfate, and effervescent granules as enteric magnetic resonance imaging (MRI) contrast agents. Five volunteers were recruited. Each volunteer ingested for examinations, separated by at least one week, either 500 ml of each of the liquid preparations or two packets of the CO2 granules (producing 400 ml of CO2 per packet). Abdominal MR images were then obtained using a 1.5 T Magnetom imager and SE 550/22, SE 2000/45/90 and FISP 40/18/40-degrees pulse sequences. The oil emulsions were best tolerated. Barium sulfate caused the greatest amount of nausea, followed by Geritol and Kaolin-pectin. With FISP 40/18/40-degrees, 60%-80% of the small bowel was well delineated using oil emulsion, Kaolin-pectin, or barium sulfate. We conclude that oil emulsion was by far the best enteric MR contrast agent in our study. Good delineation of the small bowel and pancreas can be achieved using oil emulsion and gradient echo pulse sequences. The lack of side-effects and the excellent taste make it highly acceptable to human subjects.

引用

页码：559 / 568

页数：10

共 21 条

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