MEASUREMENT OF CAFFEINE METABOLITES IN URINE USING DIODE-ARRAY DETECTION HPLC

被引：5

作者：

MICELI, JN ^{[1
]}

CHAPMAN, W ^{[1
]}

机构：

[1] MOREHOUSE COLL, SCH MED, DEPT MED, ATLANTA, GA 30314 USA

来源：

JOURNAL OF LIQUID CHROMATOGRAPHY | 1990年 / 13卷 / 11期

关键词：

D O I：

10.1080/01483919008049027

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

Diode-array detection high performance liquid chromatography (HPLC) offers significant advantages when compared to conventional UV HPLC detection. These advantages include important spectral information such as the r max and the UV spectra of each eluting peak. The spectral scans are obtained at the peak start, peak apex and peak end. This provides a comparison of these spectra so that peak homogeneity can be calculated. Standard spectra can be stored and compared to eluting peaks for “purity”. Therefore, peak identification is based not only on retention time but the aforementioned spectral information. © 1990, Taylor & Francis Group, LLC. All rights reserved.

引用

页码：2239 / 2251

页数：13

共 25 条

[1] ACETYLATOR PHENOTYPES AND TYPE-I (INSULIN-DEPENDENT) DIABETICS WITH MICRO-VASCULAR DISEASE [J].

BODANSKY, HJ ;

DRURY, PL ;

CUDWORTH, AG ;

EVANS, DAP .

DIABETES, 1981, 30 (11) :907-910

[2] DIPHENYLHYDANTOIN INTOXICATION ATTENDANT TO SLOW INACTIVATION OF ISONIAZID [J].

BRENNAN, RW ;

DEHEJIA, H ;

KUTT, H ;

VEREBELY, K ;

MCDOWELL, F .

NEUROLOGY, 1970, 20 (07) :687-&

[3] ACETYLATOR PHENOTYPE IN PATIENTS WITH BREAST-CANCER [J].

BULOVSKAYA, LN ;

KRUPKIN, RG ;

BOCHINA, TA ;

SHIPKOVA, AA ;

PAVLOVA, MV .

ONCOLOGY, 1978, 35 (04) :185-188

[4] DIABETIC DIMORPHISM ACCORDING TO ACETYLATOR STATUS [J].

BURROWS, AW ;

HOCKADAY, TDR ;

MANN, JI ;

TAYLOR, JG .

BRITISH MEDICAL JOURNAL, 1978, 1 (6107) :208-210

[5]

CARTWRIGHT RA, 1984, BANBURY REPORT, V16, P359

[6]

DAVADATTA S, 1960, B WORLD HEALTH ORGAN, V23, P587

[7] A SIMPLE TEST FOR ACETYLATOR PHENOTYPE USING CAFFEINE [J].

GRANT, DM ;

TANG, BK ;

KALOW, W .

BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 1984, 17 (04) :459-464

[8] POLYMORPHIC N-ACETYLATION OF A CAFFEINE METABOLITE [J].

GRANT, DM ;

TANG, BK ;

KALOW, W .

CLINICAL PHARMACOLOGY & THERAPEUTICS, 1983, 33 (03) :355-359

[9] ACETYLATOR GENOTYPE AND ARYLAMINE-INDUCED CARCINOGENESIS [J].

HEIN, DW .

BIOCHIMICA ET BIOPHYSICA ACTA, 1988, 948 (01) :37-66

[10]

HENNINGSEN NC, 1975, ACTA MED SCAND, V198, P475

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