ASSIGNMENT OF THE HUMAN BETA-TROPOMYOSIN GENE (TPM2) TO BAND 9P13 BY FLUORESCENCE IN-SITU HYBRIDIZATION

被引：8

作者：

HUNT, CCJ

EYRE, HJ

AKKARI, PA

MEREDITH, C

DOROSZ, SM

WILTON, SD

CALLEN, DF

LAING, NG

BAKER, E

机构：

[1] AUSTRALIAN NEUROMUSC RES INST,QUEEN ELIZABETH II MED CTR,NEDLANDS,WA 6009,AUSTRALIA

[2] EDITH COWAN UNIV,JOONDALUP,WA,AUSTRALIA

[3] WOMENS & CHILDRENS HOSP,CTR GENET MED,DEPT CYTOGENET & MOLEC GENET,ADELAIDE,SA,AUSTRALIA

来源：

CYTOGENETICS AND CELL GENETICS | 1995年 / 71卷 / 01期

关键词：

D O I：

10.1159/000134070

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

A sequence tagged site (STS) was developed for the human beta tropomyosin gene (TPM2). The STS was used to amplify DNA from somatic cell hybrids to localise TPM2 to human chromosome 9. Genomic clones isolated with the STS product were in turn used in fluorescence in situ hybridisation to metaphase chromosome spreads to further localise TPM2 to 9p13.

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收藏

页码：94 / 95

页数：2

相关论文

共 10 条

[1] ORGANIZATION OF THE HTMNM GENE - IMPLICATIONS FOR THE EVOLUTION OF MUSCLE AND NON-MUSCLE TROPOMYOSINS [J].

CLAYTON, L ;

REINACH, FC ;

CHUMBLEY, GM ;

MACLEOD, AR .

JOURNAL OF MOLECULAR BIOLOGY, 1988, 201 (03) :507-515

[2]

DUBOIS BL, 1992, GENOMICS, V16, P315

[3] ASSIGNMENT OF THE HUMAN SKELETAL-MUSCLE ALPHA-TROPOMYOSIN GENE (TPM1) TO BAND 15Q22 BY FLUORESCENCE IN-SITU HYBRIDIZATION [J].

EYRE, H ;

AKKARI, PA ;

WILTON, SD ;

CALLEN, DC ;

BAKER, E ;

LAING, NG .

CYTOGENETICS AND CELL GENETICS, 1995, 69 (1-2) :15-17

[4] ASSIGNMENT OF THE HUMAN SLOW SKELETAL-MUSCLE TROPONIN GENE (TNNI1) TO 1Q32 BY FLUORESCENCE INSITU HYBRIDIZATION [J].

EYRE, HJ ;

AKKARI, PA ;

MEREDITH, C ;

WILTON, SD ;

CALLEN, DC ;

KEDES, L ;

LAING, NG .

CYTOGENETICS AND CELL GENETICS, 1993, 62 (2-3) :181-182

[5] A MUTATION IN THE ALPHA-TROPOMYOSIN GENE TPM3 ASSOCIATED WITH AUTOSOMAL-DOMINANT NEMALINE MYOPATHY [J].

LAING, NG ;

WILTON, SD ;

AKKARI, PA ;

DOROSZ, S ;

BOUNDY, K ;

KNEEBONE, C ;

BLUMBERGS, P ;

WHITE, S ;

WATKINS, H ;

LOVE, DR ;

HAAN, E .

NATURE GENETICS, 1995, 9 (01) :75-79

[6] A COMMON LANGUAGE FOR PHYSICAL MAPPING OF THE HUMAN GENOME [J].

OLSON, M ;

HOOD, L ;

CANTOR, C ;

BOTSTEIN, D .

SCIENCE, 1989, 245 (4925) :1434-1435

[7]

Sambrook J., 1989, MOL CLONING

[8] ALPHA-TROPOMYOSIN AND CARDIAC TROPONIN-T MUTATIONS CAUSE FAMILIAL HYPERTROPHIC CARDIOMYOPATHY - A DISEASE OF THE SARCOMERE [J].

THIERFELDER, L ;

WATKINS, H ;

MACRAE, C ;

LAMAS, R ;

MCKENNA, W ;

VOSBERG, HP ;

SEIDMAN, JG ;

SEIDMAN, CE .

CELL, 1994, 77 (05) :701-712

[9] COMPLETE NUCLEOTIDE-SEQUENCE OF THE ADULT SKELETAL ISOFORM OF HUMAN SKELETAL-MUSCLE BETA-TROPOMYOSIN [J].

WIDADA, JS ;

FERRAZ, C ;

CAPONY, JP ;

LIAUTARD, JP .

NUCLEIC ACIDS RESEARCH, 1988, 16 (07) :3109-3109

[10]

WILTON SD, 1994, CYTOGENET CELL GENET, V68, P122