AUTOMATED SYNTHESIS OF [F-18] FDG USING TETRABUTYLAMMONIUM BICARBONATE

被引：23

作者：

CULBERT, PA ^{[1
]}

ADAM, MJ ^{[1
]}

HURTADO, ET ^{[1
]}

HUSER, JMA ^{[1
]}

JIVAN, S ^{[1
]}

LU, J ^{[1
]}

RUTH, TJ ^{[1
]}

ZEISLER, SK ^{[1
]}

机构：

[1] UNIV BRITISH COLUMBIA,TRIUMF,PROGRAM POSITRON EMISS TOMOG,VANCOUVER,BC V6T 2A3,CANADA

来源：

APPLIED RADIATION AND ISOTOPES | 1995年 / 46卷 / 09期

基金：

英国医学研究理事会;

关键词：

D O I：

10.1016/0969-8043(95)00177-F

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The synthesis of [F-18]FDG using tetrabutylammonium bicarbonate has been successfully modified to accommodate automation using the Optomux(R) control system. Noteworthy changes to the methods previously reported are the addition of a small ion exchange column which serves to quantitatively trap [F-18]fluoride from the target water and the extensive use of thermocouple and radiation detector feedback for process control. The radiochemical yields observed over 30 runs are: 50.3 +/- 9% decay corrected and 34.6 +/- 6% decay uncorrected.

引用

页码：887 / 891

页数：5