ESTIMATION OF SENSITIVITY AND SPECIFICITY OF SITE-SPECIFIC DIAGNOSTIC-TESTS

被引:33
作者
HUJOEL, PP [1 ]
MOULTON, LH [1 ]
LOESCHE, WJ [1 ]
机构
[1] UNIV MICHIGAN,SCH DENT,DEPT BIOL & MAT SCI,ANN ARBOR,MI 48109
关键词
D O I
10.1111/j.1600-0765.1990.tb00903.x
中图分类号
R78 [口腔科学];
学科分类号
1003 ;
摘要
Clinical trials designed to estimate the sensitivity and specificity of periodontal diagnostic tests often use multiple sites per patient as experimental units of analyses. Since site‐specific test results within a patient are dependent observations, a correlated binomial model should be employed to estimate the sensitivity and specificity of these diagnostic tests. Ignoring the within‐patient correlation can result in an over‐ or underestimation of the true standard errors. Copyright © 1990, Wiley Blackwell. All rights reserved
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页码:193 / 196
页数:4
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