BROMOMETRIC ASSAY OF CYCLOPENTOBARBITAL

被引：4

作者：

ERNST, L

GORLITZER, K

BOVENTER, K

机构：

[1] TECH UNIV BRAUNSCHWEIG,INST PHARMAZEUT CHEM,W-3300 BRAUNSCHWEIG,GERMANY

[2] FREE UNIV BERLIN,INST PHARM,W-1000 BERLIN 33,GERMANY

来源：

ARCHIV DER PHARMAZIE | 1990年 / 323卷 / 06期

关键词：

D O I：

10.1002/ardp.19903230608

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Racemisches Cyclopentobarbital liefert bei der Bromierung in Eisessig/HCl das Gemisch zweier epimerer 5‐(2,3‐Dibrompropyl)‐5‐(3‐brom‐2‐hydroxycyclopentyl)‐barbitursäuren (4). Mit Brom in Methanol entsteht ein 7,8‐Cyclopenta‐9,10‐dioxa‐2,4‐diaza[4.3.3]propellan 12. Zum Strukturbeweis wurden die 1H‐ und 13C‐NMR‐Spektren durch 2D‐Techniken vollständig zugeordnet. Copyright © 1990 WILEY‐VCH Verlag GmbH & Co. KGaA, Weinheim

引用

页码：361 / 366

页数：6

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