LIPASE-CATALYZED RESOLUTION OF 2-SUBSTITUTED 3-CYCLOPENTEN-1-OL DERIVATIVES

被引：4

作者：

SAKAI, T

IIDA, Y

KIKUYAMA, S

TSUBOI, S

UTAKA, M

机构：

来源：

CHEMISTRY LETTERS | 1991年 / 09期

关键词：

D O I：

10.1246/cl.1991.1651

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

2-Oxabicyclo[3.3.0]oct-6-en-3-one, the key intermediate in the prostaglandin synthsis, was subjected to the optical resolution effectively by use of lipase after conversion to 2-[2-(t-butyldimetylsilyloxy)ethyl]-3-cyclopenten-1-yl acetate and 2-[2-(N,N-dimethylcarbamoyl)methyl]-3-cylopenten-1-yl acetate.

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页码：1651 / 1652

页数：2

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