SYNTHESIS OF ERYTHRINA AND RELATED ALKALOIDS .37. CHIRAL SYNTHESIS OF ENANTIO-TYPE ERYTHRINAN ALKALOIDS UTILIZING ASYMMETRIC ACYLATION AND KINETIC RESOLUTION OF DIASTEREOMERS

被引：18

作者：

HOSOI, S ^{[1
]}

ISHIDA, K ^{[1
]}

SANGAI, M ^{[1
]}

TSUDA, Y ^{[1
]}

机构：

[1] KANAZAWA UNIV, FAC PHARMACEUT SCI, 13-1 TAKARA MACHI, KANAZAWA, ISHIKAWA 920, JAPAN

来源：

CHEMICAL & PHARMACEUTICAL BULLETIN | 1992年 / 40卷 / 11期

关键词：

D O I：

10.1248/cpb.40.3115

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Chiral synthesis of an erythrinan alkaloid, (-)-3-demethoxyerythratidinone (11), as well as a versatile intermediate, the 1,7-cycloerythrinan derivative (14) (both are or enantio-type) was achieved using asymmetric acylation and kinetic resolution starting from the L-dopa derivative (1).

引用

页码：3115 / 3117

页数：3

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