ANALYSIS OF ASSOCIATIONS BETWEEN MAJOR HISTOCOMPATIBILITY COMPLEX (BOLA) CLASS-I HAPLOTYPES AND SUBCLINICAL MASTITIS OF DAIRY-COWS

被引：29

作者：

AARESTRUP, FM ^{[1
]}

JENSEN, NE ^{[1
]}

OSTERGARD, H ^{[1
]}

机构：

[1] ROYAL VET & AGR UNIV,DEPT ANIM SCI & HLTH,COPENHAGEN,DENMARK

来源：

JOURNAL OF DAIRY SCIENCE | 1995年 / 78卷 / 08期

关键词：

MASTITIS; BOLA; MAJOR HISTOCOMPATIBILITY; STAPHYLOCOCCI;

D O I：

10.3168/jds.S0022-0302(95)76793-5

中图分类号：

S8 [畜牧、动物医学、狩猎、蚕、蜂];

学科分类号：

0905 ;

摘要：

The associations between BoLA class I haplotypes and subclinical mastitis were investigated using information on 333 cows from three different breeds and crossbreeds from 14 dairy herds in Denmark. Somatic cell count and bacteriological status were used as markers for subclinical mastitis. Associations between BoLA class I haplotypes and IMI status were also determined. The association between BoLA class I haplotypes and subclinical mastitis was weak. The A10(W50), A11, A12(A30), A16, A19(A6), A21, A26, and A31(A30) alleles were associated with different markers of subclinical mastitis. Susceptibility or resistance to the two bacteria categories was associated with different alleles. This study indicated that BoLA antigens may be involved in resistance to mastitis and that resistance may be specific for a particular pathogen.

引用

页码：1684 / 1692

页数：9

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