LEFT-VENTRICULAR MASS INDEX NEGATIVELY CORRELATES WITH HEART-RATE-VARIABILITY IN ESSENTIAL-HYPERTENSION

被引：37

作者：

KOHARA, K

HARANAKAMURA, N

HIWADA, K

机构：

[1] 2nd Department of Internal Medicine, Ehime University School of Medicine, Ehime

来源：

AMERICAN JOURNAL OF HYPERTENSION | 1995年 / 8卷 / 02期

关键词：

POWER SPECTRAL ANALYSIS; LEFT VENTRICULAR HYPERTROPHY; AUTONOMIC NERVOUS ACTIVITY; ESSENTIAL HYPERTENSION;

D O I：

10.1016/0895-7061(94)00190-M

中图分类号：

R6 [外科学];

学科分类号：

1002 ; 100210 ;

摘要：

To investigate the relationship between alterations of the autonomic nervous activity and left ventricular mass index in essential hypertensive patients, 24-h power spectral analysis of R-R intervals was performed using Holter electrocardiography. Fifty-three patients (mean age, 58.0 +/- 13.1 years; 30 men and 23 women) participated.; The urinary excretions and plasma levels of catecholamines were also determined. Power spectral analysis of R-R interval was performed every 10 min by the maximum entropy method to obtain the low frequency band (LFB; 0.04 to 0.15 Hz), which is an index of both parasympathetic and sympathetic nervous activities, and the high frequency band (HFB; 0.15 to 0.4 Hz), which reflects parasympathetic nervous activity. LFB and HFB were averaged every hour to obtain hourly LFB and HFB levels. Total LFB and HFB were calculated as the summation of 24-h LFBs and HFBs. Left ventricular mass index showed a significant negative correlation with total LFB (r = -0.466, P < .001) and total HFB (r = -0.319, P < .02). These findings suggest that the level of end-organ damage correlates with neuronal alteration in essential hypertension.

引用

页码：183 / 188

页数：6

共 25 条

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