SYNTHETIC STUDIES ON AN ANTITUMOR ANTIBIOTIC, BLEOMYCIN .17. SYNTHETIC STUDY TOWARDS MAN-DESIGNED BLEOMYCINS - SYNTHESIS OF A DNA CLEAVING MOLECULE BASED ON BLEOMYCIN

被引：41

作者：

OTSUKA, M

KITTAKA, A

OHNO, M

SUZUKI, T

KUWAHARA, J

SUGIURA, Y

UMEZAWA, H

机构：

[1] UNIV TOKYO,FAC PHARMACEUT SCI,BUNKYO KU,TOKYO 113,JAPAN

[2] KYOTO UNIV,FAC PHARMACEUT SCI,KYOTO 606,JAPAN

[3] INST MICROBIAL CHEM,SHINAGAWA KU,TOKYO 141,JAPAN

来源：

TETRAHEDRON LETTERS | 1986年 / 27卷 / 31期

关键词：

D O I：

10.1016/S0040-4039(00)84869-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

引用

页码：3639 / 3642

页数：4

共 14 条

[1] SEQUENCE-SPECIFIC CLEAVAGE OF DOUBLE-HELICAL DNA - N-BROMOACETYLDISTAMYCIN
BAKER, BF
DERVAN, PB
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1985, 107 (26) : 8266 - 8268
[2] CHIEN M, 1977, BIOCHEMISTRY-US, V18, P96
[3] (2S,3S,4R)-4-AMINO-3-HYDROXY-2-METHYLPENTANOIC ACID - ENANTIOSELECTIVE SYNTHESIS OF AN AMINO-ACID CONSTITUENT OF BLEOMYCIN
DIPARDO, RM
BOCK, MG
[J]. TETRAHEDRON LETTERS, 1983, 24 (44) : 4805 - 4808
[4] RECOGNITION AND CLEAVAGE OF DNA - FUNCTIONAL ANALOGS OF BLEOMYCIN
HASHIMOTO, Y
SHUDO, K
[J]. JOURNAL OF SYNTHETIC ORGANIC CHEMISTRY JAPAN, 1985, 43 (10) : 908 - 920
[5] CHEMISTRY OF BLEOMYCIN .22. INTERACTION OF BLEOMYCIN WITH NUCLEIC-ACIDS, PREFERENTIAL BINDING TO GUANINE BASE AND ELECTROSTATIC EFFECT OF TERMINAL AMINE
KASAI, H
UMEZAWA, H
NAGANAWA, H
TAKITA, T
[J]. JOURNAL OF ANTIBIOTICS, 1978, 31 (12) : 1316 - 1320
[6] BLEOMYCIN MODELS - HEMIN ACRIDINES WHICH BIND TO DNA AND CAUSE OXYGEN-DEPENDENT SCISSION
LOWN, JW
JOSHUA, AV
[J]. JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS, 1982, (22) : 1298 - 1300
[7] NEW AGENTS FOR TERTIARY BUTYLOXYCARBONYLATION AND PARA METHOXYBENZYL-OXYCARBONYLATION OF AMINO-ACIDS
NAGASAWA, T
KUROIWA, K
NARITA, K
ISOWA, Y
[J]. BULLETIN OF THE CHEMICAL SOCIETY OF JAPAN, 1973, 46 (04) : 1269 - 1272
[8] TRANSITION-METAL BINDING-SITE OF BLEOMYCIN - A SYNTHETIC ANALOG EQUIVALENT TO BLEOMYCIN IN ACTIVATING MOLECULAR-OXYGEN
SUGANO, Y
KITTAKA, A
OTSUKA, M
OHNO, M
SUGIURA, Y
UMEZAWA, H
[J]. TETRAHEDRON LETTERS, 1986, 27 (31) : 3635 - 3638
[9] BLEOMYCIN-IRON COMPLEXES - ELECTRON-SPIN RESONANCE STUDY, LIGAND EFFECT, AND IMPLICATION FOR ACTION MECHANISM
SUGIURA, Y
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1980, 102 (16) : 5208 - 5215
[10] COPPER-BLEOMYCIN HAS NO SIGNIFICANT DNA CLEAVAGE ACTIVITY
SUZUKI, T
KUWAHARA, J
SUGIURA, Y
[J]. BIOCHEMISTRY, 1985, 24 (18) : 4719 - 4721

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