PARALLEL COMPUTING IN BIOMEDICAL-RESEARCH

被引：31

作者：

MARTINO, RL ^{[1
]}

JOHNSON, CA ^{[1
]}

SUH, EB ^{[1
]}

TRUS, BL ^{[1
]}

YAP, TK ^{[1
]}

机构：

[1] NIAMSD,STRUCT BIOL RES LAB,BETHESDA,MD 20892

来源：

SCIENCE | 1994年 / 265卷 / 5174期

关键词：

D O I：

10.1126/science.8052847

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Scalable parallel computer architectures provide the computational performance needed for advanced biomedical computing problems. The National Institutes of Health have developed a number of parallel algorithms and techniques useful in determining biological structure and function. These applications include processing electron micrographs to determine the three-dimensional structure of viruses, calculating the solvent-accessible surface area of proteins to help predict the three-dimensional conformation of these molecules from their primary structures, and searching for homologous DNA or amino acid sequences in large biological databases. Timing results demonstrate substantial performance improvements with parallel implementations compared with conventional sequential systems.

引用

页码：902 / 908

页数：7

共 28 条

[1]

Almasi GS., 1994, HIGHLY PARALLEL COMP

[2] PRINCIPLES THAT GOVERN FOLDING OF PROTEIN CHAINS [J].