SYNTHESIS OF 2 TETRAPHENYLANTIMONY COMPLEXES OF PYRIDINE-N-OXIDES - CRYSTAL-STRUCTURE OF TETRAPHENYLANTIMONY (2-MERCAPTOPYRIDINE-N-OXIDE)

Tetraphenylantimony(2-mercaptopyridine-N-oxide) and tetraphenylantimony(2-selenopyridine-N-oxide) were synthesized from tetraphenylantimonybromide and the appropriate pyridine-N-oxide derivative. X-ray crystal structure analysis shows that the former compound crystallizes in space group C2/c, with a 29.095(2), b 10.6965(8), c 18.134(1), beta 94.154(5) and Z 8. The mercaptopyridine-N-oxide ligand binds via both its sulfur and oxygen atoms, leading to a distorted octahedral geometry about the antimony atom. Tetraphenylantimonypyridine-N-oxide derivatives of sulfur and selenium were found to possess antimalarial activity.