TRITERPENES OF PORIA-COCOS

被引：95

作者：

TAI, T ^{[1
]}

AKAHORI, A ^{[1
]}

SHINGU, T ^{[1
]}

机构：

[1] KOBEGAKUIN UNIV,FAC PHARMACEUT SCI,NISHI KU,KOBE 65121,JAPAN

来源：

PHYTOCHEMISTRY | 1993年 / 32卷 / 05期

关键词：

PORIA-COCOS; BASIDIOMYCETES; EBURICOIC ACID; DEHYDROEBURICOIC ACID; TRAMETENOLIC ACID; 3-BETA-HYDROXYLANOSTA-7,9(11),24-TRIEN-21-OIC ACID; N-CHLOROMETHYLPHTHALIMIDE; PORICOIC ACID-C; D; PORICOIC ACID DM; AM;

D O I：

10.1016/S0031-9422(00)95099-4

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Four lanostane triterpenes and four novel 3,4-seco-lanostane triterpenes were isolated from the surface layer of Poria cocos. 3beta-Hydroxylanosta-7,9(11),24-trien-21-oic acid, trametenolic acid, dehydroeburicoic acid and eburicoic acid were isolated by HPLC after treatment with N-chloromethylphthalimide. Four novel 3,4-seco-lanostanes: poricoic acid C, D, DM and AM were isolated by HPLC methods. Their structures are, respectively, 3,4-seco-lanosta-4(28),7,9(11),24(31)-tetraen-3,21-dioic acid and 16alpha,25-dihydroxy-3,4-seco-lanosta-4(28),7,9(11),24(31)-tetraen-3,21-dioic acid, 16alpha,25-dihydroxy-3,4-seco-lanosta-4(28),7,9(11),24(31)-tetraen-3,21-dioic acid 3-methyl ester and 16alpha-hydroxy-3,4-seco-lanosta-4(28),7,9(11),24(31)-tetraen-3,21-dioic acid 3-methyl ester, from spectroscopic evidence.

引用

页码：1239 / 1244

页数：6

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