EFFECT OF HALOTHANE ON SPINAL SOMATOSENSORY EVOKED-POTENTIALS IN SHEEP

被引:13
作者
BAINES, DB [1 ]
WHITTLE, IR [1 ]
CHASELING, RW [1 ]
OVERTON, JH [1 ]
JOHNSTON, IH [1 ]
机构
[1] ROYAL ALEXANDRA HOSP CHILDREN, DEPT NEUROSURG, CAMPERDOWN, NSW 2050, AUSTRALIA
关键词
D O I
10.1093/bja/57.9.896
中图分类号
R614 [麻醉学];
学科分类号
100217 ;
摘要
The effects of increasing concentrations of halothane on the morphology of spinal somatosensory evoked potentials (SEP) were studied in seven anaesthetized sheep. Anaesthesia was induced with thiopentone and maintained with nitrousoxide in oxygen. Ventilation was controlled throughout. Arterial pressure, temperature and end-tidal carbon dioxide tension were monitored. A lumbar laminectomy was performed, the sciatic nerve exposed and a baseline spinal SEP was recorded from the surface of the lumbar spinal cord. Halothane was introduced in incremental steps of 1% up to 3% and further SEP were recorded. These recordings revealed that the spinal SEP peak latencies and general waveform configuration were stable under halothane anaesthesia. Baselne SEP amplitude was similar to that obtained with 1% halothane; however, at concentrations of 2% halothane or greater, there was a significant (P < 0.005) attenuation of all components of the spinal SEP. These findings have important anaesthetic implications for patients undergoing spinal cord monitoring using SEP, although interspecies differences may occur.
引用
收藏
页码:896 / 899
页数:4
相关论文
共 12 条
[1]   EFFECTS OF COMPRESSION AND ISCHEMIA ON SPINAL-CORD EVOKED-POTENTIALS [J].
BENNETT, MH .
EXPERIMENTAL NEUROLOGY, 1983, 80 (03) :508-519
[2]   CURRENT CONCEPTS REVIEW - SPINAL-CORD MONITORING [J].
BUNCH, WH ;
SCARFF, TB ;
TRIMBLE, J .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1983, 65 (05) :707-710
[3]   NEUROPHYSIOLOGIC EFFECTS OF GENERAL ANESTHETICS .1. ELECTROENCEPHALOGRAM AND SENSORY EVOKED-RESPONSES IN MAN [J].
CLARK, DL ;
ROSNER, BS .
ANESTHESIOLOGY, 1973, 38 (06) :564-582
[4]   SOMATOSENSORY EVOKED-POTENTIALS DURING HARRINGTON INSTRUMENTATION FOR SCOLIOSIS [J].
ENGLER, GL ;
SPIELHOLZ, NI ;
BERNHARD, WN ;
DANZIGER, F ;
MERKIN, H ;
WOLFF, T .
JOURNAL OF BONE AND JOINT SURGERY-AMERICAN VOLUME, 1978, 60 (04) :528-532
[5]   INTRAOPERATIVE MONITORING OF SENSORY-EVOKED POTENTIALS [J].
GRUNDY, BL .
ANESTHESIOLOGY, 1983, 58 (01) :72-87
[6]   A SYSTEM FOR THE ELECTRO-PHYSIOLOGICAL MONITORING OF THE SPINAL-CORD DURING OPERATIONS FOR SCOLIOSIS [J].
JONES, SJ ;
EDGAR, MA ;
RANSFORD, AO ;
THOMAS, NP .
JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME, 1983, 65 (02) :134-139
[7]   SPINAL-CORD MONITORING DURING SPINAL SURGERY USING SOMATOSENSORY SPINAL EVOKED-POTENTIALS [J].
LAMONT, RL ;
WASSON, SL ;
GREEN, MA .
JOURNAL OF PEDIATRIC ORTHOPAEDICS, 1983, 3 (01) :31-36
[8]   SPINAL-CORD MONITORING USING EVOKED-POTENTIALS RECORDED FROM FELINE VERTEBRAL BONE [J].
NORDWALL, A ;
AXELGAARD, J ;
HARADA, Y ;
VALENCIA, P ;
MCNEAL, DR ;
BROWN, JC .
SPINE, 1979, 4 (06) :486-494
[9]   INTRAOPERATIVE MONITORING OF EVOKED-POTENTIALS [J].
RAUDZENS, PA .
ANNALS OF THE NEW YORK ACADEMY OF SCIENCES, 1982, 388 (JUN) :308-326
[10]   EFFECTS OF HALOTHANE OR ENFLURANE WITH CONTROLLED VENTILATION ON AUDITORY EVOKED-POTENTIALS [J].
THORNTON, C ;
HENEGHAN, CPH ;
JAMES, MFM ;
JONES, JG .
BRITISH JOURNAL OF ANAESTHESIA, 1984, 56 (04) :315-323