DETECTING GENE CONVERSION - PRIMATE VISUAL PIGMENT GENES

被引：28

作者：

BALDING, DJ ^{[1
]}

NICHOLS, RA ^{[1
]}

HUNT, DM ^{[1
]}

机构：

[1] UNIV LONDON, QUEEN MARY & WESTFIELD COLL, SCH BIOL SCI, LONDON E1 4NS, ENGLAND

来源：

PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES | 1992年 / 249卷 / 1326期

关键词：

D O I：

10.1098/rspb.1992.0114

中图分类号：

Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The effects of gene conversion can be detected in the DNA sequences of multigene families. We develop a permutation test of the significance of patterns of sequence mismatches, and apply it to the sequences of the red- and green-sensitive visual pigment genes of human and the diana monkey. Whereas conventional tests of the rate of sequence divergence are equivocal, the permutation test convincingly excludes divergence in the absence of gene conversion (p = 10(-6)).

引用

页码：275 / 280

页数：6

共 29 条

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