ADDITIONAL COPIES OF 1Q IN SEQUENTIAL SAMPLES FROM A PHYLLODES TUMOR OF THE BREAST

被引：11

作者：

BIRDSALL, SH ^{[1
]}

SUMMERSGILL, BM ^{[1
]}

EGAN, M ^{[1
]}

FENTIMAN, IS ^{[1
]}

GUSTERSON, BA ^{[1
]}

SHIPLEY, JM ^{[1
]}

机构：

[1] GUYS HOSP,IMPERIAL CANC RES FUND,CLIN ONCOL UNIT,LONDON SE1 9RT,ENGLAND

来源：

CANCER GENETICS AND CYTOGENETICS | 1995年 / 83卷 / 02期

关键词：

D O I：

10.1016/0165-4608(95)00072-W

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Cytogenetic and fluorescent in situ hybridization (FISH) analysis has been performed on consecutive samples, taken 4 weeks apart, from a phyllodes breast tumor. This revealed the presence of two different chromosome 1 derivatives, namely a dic(1;10)(q10;q24) in the first sample and an i(1)(q10) in the second. In one cell out of 25 from the second sample both derivative chromosomes were seen. A chromosome 21 was lost in both samples. These results are consistent with phyllodes tumors having a clonal origin.

引用

页码：111 / 114

页数：4

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