SELF-TREATMENT OF FEMALE EXTERNAL GENITAL WARTS WITH 0.5-PERCENT PODOPHYLLOTOXIN CREAM (CONDYLINE(R)) VS WEEKLY APPLICATIONS OF 20-PERCENT PODOPHYLLIN SOLUTION

被引：26

作者：

HELLBERG, D

SVARRER, T

NILSSON, S

VALENTIN, J

机构：

[1] Department of Obstetrics and Gynecology, Falun Hospital, Falun

[2] Swedish Radiation Protection Institute, Stockholm

来源：

INTERNATIONAL JOURNAL OF STD & AIDS | 1995年 / 6卷 / 04期

关键词：

FEMALE GENITAL WARTS; PODOPHYLLOTOXIN CREAM; PODOPHYLLIN SOLUTION;

D O I：

10.1177/095646249500600407

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Sixty women with genital warts were randomly allocated to treatment with either weekly application of 20% podophyllin solution or self-treatment with 0.5% podophyllotoxin cream twice daily for three days in weekly intervals. After a maximum of 4 treatment cycles a final assessment was carried out after 3 months. Primary clearance after termination of treatment was 82% for podophyllotoxin and 59% for podophyllin solution. After excluding relapses at the 3-month follow-up, final clearance for podophyllotoxin (71%) was significantly better (P<0.05) than that for podophyllin solution (48%). The total frequency of warts eradicated was 94% with podophyllotoxin and 74% with podophyllin solution (P<0.001). Local adverse effects were generally mild or moderate. Podophyllotoxin cream provides a mode of easy application for women with external genital warts and had in this study a significantly better effect than podophyllin solution.

引用

页码：257 / 261

页数：5

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