A NEW BIND FOR MYC

被引:46
作者
PRENDERGAST, GC
ZIFF, EB
机构
[1] NYU MED CTR, HOWARD HUGHES MED INST, KAPLAN CANC CTR, NEW YORK, NY 10016 USA
[2] NYU MED CTR, DEPT BIOCHEM, NEW YORK, NY 10016 USA
关键词
D O I
10.1016/0168-9525(92)90062-9
中图分类号
Q3 [遗传学];
学科分类号
071007 ; 090102 ;
摘要
Recent studies centered on the c-Myc basic/helix-loop-helix/leucine zipper (B/HLH/LZ) motifs have led to the identification of a DNA recognition sequence for c-Myc and the isolation of a novel protein that forms a DNA-binding complex with c-Myc in vitro. These advances may make it possible to address directly the long-standing question of c-Myc function in vivo.
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页码:91 / 96
页数:6
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