CORRELATION OF END-TIDAL CO2 MEASUREMENTS TO ARTERIAL PACO(2) IN NONINTUBATED PATIENTS

被引:79
作者
BARTON, CW
WANG, ESJ
机构
[1] Division of Emergency Medicine, University of California, San Francisco
关键词
D O I
10.1016/S0196-0644(94)70078-8
中图分类号
R4 [临床医学];
学科分类号
1002 ; 100602 ;
摘要
Study objective: To determine the accuracy of end-tidal carbon dioxide levels as a measure of arterial carbon dioxide levels in non-intubated patients presenting to an emergency department for care. Design: A prospective, cross-sectional analysis. Setting: University hospital ED. Type of participant: Nonintubated adult patients presenting to the ED for care of a variety of problems. Interventions: Patients who had arterial blood gas samples taken as part of their ED evaluation were asked to breathe normally through an endotracheal tube adapter or a modified nasal cannula connected to a side port sampling capnometer while a sample for arterial blood gas was drawn from the radial artery. Measurements: End-tidal carbon dioxide levels (mm Hg) were recorded at the time of arterial blood gas sampling. The difference between end-tidal carbon dioxide and PaCO2 was tested with the paired t-test at a significance level of .05. The correlation of end-tidal carbon dioxide to PaCO2 was tested in all patients and in subgroups using simple linear regression. Results: Seventy-six patients were enrolled. In all patients, end-tidal carbon dioxide was 3.5 mm Hg lower than Paco2 and correlated well with PaCO2 (r2 = .772). In patients with hypocapnia, there was no significant difference between end-tidal carbon dioxide and PaCO2 (P = .17), and the correlation of end-tidal carbon dioxide to PaCO2 was stronger (r2 = .838). In patients with a respiratory or metabolic acidosis, the difference between end-tidal carbon dioxide and PaCO2 was 6 mm Hg (P = .005), but end-tidal carbon dioxide correlated well to PaCO2 (r2 = .899). Conclusion: Measurements of end-tidal carbon dioxide concentrations correlate well with PaCO2 values in nonintubated patients presenting with a variety of conditions to EDs. End-tidal carbon dioxide measurements may be sufficient measures of PaCO2 in selected patients and obviate the need for repeat arterial blood gas determination. Further study is warranted.
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页码:560 / 563
页数:4
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