2 DIFFERENT MICROTUBULE-BASED MOTOR ACTIVITIES WITH OPPOSITE POLARITIES IN KINETOCHORES

被引:177
作者
HYMAN, AA
MITCHISON, TJ
机构
[1] Department of Pharmacology, University of California at San Francisco, San Francisco
关键词
D O I
10.1038/351206a0
中图分类号
O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];
学科分类号
07 ; 0710 ; 09 ;
摘要
The movement of microtubules on the kinetochores of isolated chromosomes has been examined by video microscopy. Two different microtubule-based motors on the kinetochore were identified, which have opposite directions of movement. The activities of these two motors can be regulated by factors that can influence phosphorylation.
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页码:206 / 211
页数:6
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