MEASUREMENT OF TOLUENE AND XYLENE METABOLITES BY GAS-CHROMATOGRAPHY

被引:39
作者
ENGSTROM, K [1 ]
HUSMAN, K [1 ]
RANTANEN, J [1 ]
机构
[1] INST OCCUPAT HLTH, DEPT TOXICOL & BIOCHEM, HAARTMANINKATU 1, SF-00290 HELSINKI, FINLAND
关键词
D O I
10.1007/BF00378270
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
A new method for analyzing urinary hippuric and methylhipuric acids by gas chromatography was developed. The direct analysis of hippuric acids and the determination of their alkaline hydrolytic products, benzoic and toluic acids, are described. Results of the 2 different methods are compared and discussed. The method was applied to workers occupationally exposed to paints containing mainly toluene and xylene. The uninary hippuric acid concentrations were related to the level of toluene and xylene in blood.
引用
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页码:153 / 160
页数:8
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