IMPAIRED FETAL BLOOD-GAS STATUS IN POLYHYDRAMNIOS AND ITS RELATION TO RAISED AMNIOTIC PRESSURE

被引：42

作者：

FISK, NM

VAUGHAN, J

TALBERT, D

机构：

[1] Royal Postgraduate Medical School, Institute of Obstetrics and Gynaecology, Queen Charlotte’s and Chelsea Hospital, London

来源：

FETAL DIAGNOSIS AND THERAPY | 1994年 / 9卷 / 01期

关键词：

POLYHYDRAMNIOS; AMNIOTIC PRESSURE; UTEROPLACENTAL PERFUSION; FETAL BLOOD GAS STATUS;

D O I：

10.1159/000263900

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

A substantial proportion of perinatal losses in polyhydramnios occur as unexplained normally formed stillbirths. In order to investigate the relationship between fetal condition and raised amniotic pressure (AP), fetal blood gas and acid-base status were determined together with AP in 22 pregnancies with polyhydramnios. At fetal blood sampling, 8 (36%) had a venous pH value and 16 (73%) a pO(2) value below the reference range. Both fetal pH and pO(2) were significantly negatively correlated with the degree of elevation in AP (y = 7.43 -0.036x, r = 0.56, p = 0.006, where y = pH and x = AP z score, and y = -1.6 - 0.48x, r = 0.54, p = O.O1, where y = pO(2) z score, respectively). Although some of these fetuses were hydropic, had congenital anomalies, or were from multiple pregnancies, univariate and multiple logistic regression analyses indicated that the above associations could not be accounted for by these potentially confounding variables. This work suggests that abnormal fetal blood gas status in human pregnancies with polyhydramnios is associated with elevated AP.

引用

页码：7 / 13

页数：7

共 28 条

[1]

Moya F., Apgar V., James L.S., Berrien C., Hydramnios and congenital anomalies, JAMA, 173, pp. 1552-1556, (1960)

[2]

Queenan J.T., Gadow E.C., Polyhydramnios: Chronic versus acute, Am J Obstet Gynecol, 108, pp. 22-25, (1970)

[3]

Hill L.M., Breckle R., Thomas M.L., Fries J.K., Polyhydramnios: Ultra-sonically detected prevalence and neonatal outcome, Obstet Gynecol, 69, pp. 21-25, (1987)

[4]

Carlson D.H., Platt L.D., Medaris A.L., Horenstcin J., Quantifiable polyhydramnios: Diagnosis and management, Obstet Gynecol, 75, pp. 989-993, (1990)

[5]

Barry A.P., Hydramnios. A survey of 100 cases, Irish J Med Sci, 331, pp. 257-264, (1953)

[6]

Hashimoto B., Callen P.W., Filly R.A., Laros R.K., Ultrasound evaluation of polyhydramnios and twin pregnancy, Am J Obstet Gynecol, 154, pp. 1069-1072, (1984)

[7]

Boylan P., Parisi V., An overivew of hydramnios, Semin Perinatol, 10, pp. 136-141, (1986)

[8]

Cardwell M.S., Polyhydramnios: A review, Obstet Gynecol Surv, 42, pp. 612-617, (1987)

[9]

Barkin S.Z., Pretorius D.H., Beckett M.K., Manchester D.K., Nelson T.R., Manco-Johnson M.L., Severe polyhydramnios: Incidence of anomalies, AJR, 148, pp. 155-159, (1987)

[10]

Pretorius D.H., Manchester D., Barkin S., Parker S.S., Nelson T.R., Doppler ultrasound of twin twin transfusion syndrome, J Ultrasound Med, 7, pp. 117-124, (1988)

← 1 2 3 →