CATHARANTHUS-ROSEUS ENZYME MEDIATED SYNTHESIS OF 3-HYDROXYVOAFRINE-A AND 3-HYDROXYVOAFRINE-B - A SIMPLE ROUTE TO THE VOAFRINES

被引：10

作者：

FAHN, W ^{[1
]}

KAISER, V ^{[1
]}

SCHUBEL, H ^{[1
]}

STOCKIGT, J ^{[1
]}

DANIELI, B ^{[1
]}

机构：

[1] UNIV MILAN,FAC SCI,DIPARTIMENTO CHIM ORGAN & IND,CNR,CTR STUDIO SOSTANZE ORGAN NAT,I-20133 MILAN,ITALY

来源：

PHYTOCHEMISTRY | 1990年 / 29卷 / 01期

关键词：

3-hydroxyvoafrine; Apocynaceae; Catharanthus roseus; dimeric indole alkaloids; enzyme mediated synthesis; tabersonine; voafrine;

D O I：

10.1016/0031-9422(90)89025-5

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Dimerization of tabersonine by a crude enzyme preparation from Catharanthus roseus led to the novel 3-hydroxyvoafrines A and B which were reduced enzymatically or chemically to the voafrines A and B, recently isolated in trace amounts from cell cultures of Voacanga africana. © 1990.

引用

页码：127 / 133

页数：7

共 12 条

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