DIFFERENT TIME COURSES OF THE BLOCKADE OF SODIUM CURRENT BY LIGNOCAINE AND SUN-1165 IN SINGLE MYOCYTES ISOLATED FROM GUINEA-PIG ATRIUM

被引：13

作者：

INOMATA, N

ISHIHARA, T

AKAIKE, N

机构：

[1] SUNTORY INST BIOMED RES,MOLEC PHARMACOL LAB,SHIMAMOTO CHO,OSAKA 618,JAPAN

[2] TOHOKU UNIV,SCH MED,DEPT NEUROPHYSIOL,SENDAI,MIYAGI 980,JAPAN

来源：

BRITISH JOURNAL OF PHARMACOLOGY | 1989年 / 98卷 / 01期

关键词：

D O I：

10.1111/j.1476-5381.1989.tb16875.x

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：149 / 154

页数：6

共 23 条

[1]

AISAKA K, 1985, ARZNEIMITTEL-FORSCH, V35-2, P1239

[2] CONCENTRATION-CLAMP STUDY OF GAMMA-AMINOBUTYRIC-ACID-INDUCED CHLORIDE CURRENT KINETICS IN FROG SENSORY NEURONS [J].

AKAIKE, N ;

INOUE, M ;

KRISHTAL, OA .

JOURNAL OF PHYSIOLOGY-LONDON, 1986, 379 :171-185

[3] KINETICS OF ONSET OF RATE-DEPENDENT EFFECTS OF CLASS-I ANTI-ARRHYTHMIC DRUGS ARE IMPORTANT IN DETERMINING THEIR EFFECTS ON REFRACTORINESS IN GUINEA-PIG VENTRICLE, AND PROVIDE A THEORETICAL BASIS FOR THEIR SUBCLASSIFICATION [J].

CAMPBELL, TJ .

CARDIOVASCULAR RESEARCH, 1983, 17 (06) :344-352

[4]

CATTERALL WA, 1978, J BIOL CHEM, V253, P7393

[5] EFFECT OF SUN-1165, A NEW POTENT ANTIARRHYTHMIC AGENT, ON THE KINETICS OF RATE-DEPENDENT BLOCK OF NA CHANNELS AND VENTRICULAR CONDUCTION OF EXTRASYSTOLES [J].

HATTORI, Y ;

HIDAKA, T ;

AISAKA, K ;

SATOH, F ;

ISHIHARA, T .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1988, 11 (04) :407-412

[6] ELECTROPHYSIOLOGICAL ACTIONS OF N-(2,6-DIMETHYLPHENYL)-8-PYRROLIZIDINE-ACETAMIDE HYDROCHLORIDE HEMIHYDRATE (SUN 1165), A NEW ANTIARRHYTHMIC AGENT [J].

HATTORI, Y ;

INOMATA, N ;

AISAKA, K ;

ISHIHARA, T .

JOURNAL OF CARDIOVASCULAR PHARMACOLOGY, 1986, 8 (05) :998-1002

[7]

HIDAKA T, 1985, ARZNEIMITTEL-FORSCH, V35-2, P1381

[8] ANTIARRHYTHMIC AGENTS - THE MODULATED RECEPTOR MECHANISM OF ACTION OF SODIUM AND CALCIUM CHANNEL-BLOCKING DRUGS [J].

HONDEGHEM, LM ;

KATZUNG, BG .

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY, 1984, 24 :387-423

[9] SUN-1165 - A NEW ANTIARRHYTHMIC NA CURRENT BLOCKER IN VENTRICULAR MYOCYTES OF GUINEA-PIG [J].

INOMATA, N ;

ISHIHARA, T ;

AKAIKE, N .

COMPARATIVE BIOCHEMISTRY AND PHYSIOLOGY C-PHARMACOLOGY TOXICOLOGY & ENDOCRINOLOGY, 1987, 87 (02) :237-243

[10] MECHANISM OF INHIBITION BY SUN-1165, A NEW NA CHANNEL BLOCKING ANTIARRHYTHMIC AGENT, OF CARDIAC GLYCOSIDE-INDUCED TRIGGERED ACTIVITY [J].

INOMATA, N ;

ISHIHARA, T .

EUROPEAN JOURNAL OF PHARMACOLOGY, 1988, 145 (03) :313-322

← 1 2 3 →