THE TIME-DEPENDENCE OF COHERENCE TRANSFER IN HOMONUCLEAR ISOTROPIC MIXING EXPERIMENTS

被引:60
作者
CAVANAGH, J
CHAZIN, WJ
RANCE, M
机构
[1] Department of Molecular Biology, Research Institute, Scripps Clinic, La Jolla, CA 92037
来源
JOURNAL OF MAGNETIC RESONANCE | 1990年 / 87卷 / 01期
关键词
D O I
10.1016/0022-2364(90)90089-R
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
The fundamental behavior of coherence transfer in isotropic mixing experiments (TOCSY or HOHAHA) is examined. A numerical simulation program has been written to calculate the time dependence of coherence transfer under the isotropic scalar coupling interaction for arbitrary spin systems. Results are shown for a variety of amino acids and for deoxyribose, which should facilitate the selection of optimum mixing times in practical applications of the TOCSY experiment. © 1990.
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页码:110 / 131
页数:22
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