2 NEW 6-ALKYLCOUMARINS FROM ANGELICA-PUBESCENS F BISERRATA

被引:17
作者
LIU, JH
XU, SX
YAO, XS
KOBAYASHI, H
机构
[1] SHENYANG PHARMACEUT UNIV,DEPT PHYTOCHEM,SHENYANG,PEOPLES R CHINA
[2] UNIV TOKYO,INST APPL MICROBIOL,TOKYO 113,JAPAN
关键词
D O I
10.1055/s-2006-958145
中图分类号
Q94 [植物学];
学科分类号
071001 ;
摘要
Two new 6-alkylcoumarins, angelitriol(1) and angelol J (2), were isolated from the EtOAc-soluble fraction of the roots of Angelica pubescens Maxim f. biserrata Shan et Yuan. Their structures were elucidated as 6-[(1R,2S)-1,2,3-trihydroxy-3-methylbutyl]-7-methoxycoumarin (1) and 6-[(1R,2R)-1-ethoxy-2,3-dihydroxy-3-methylbutyl]-7-methoxycoumarin (2), respectively, on the basis of spectral evidence. Both of them showed strong inhibitory effects on human platelet aggregation.
引用
收藏
页码:482 / 484
页数:3
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