DICTYOPTERIN, 6-(D-THREO-1,2-DIHYDROXYPROPYL)-PTERIN, A NEW NATURAL ISOMER OF L-BIOPTERIN - ISOLATION FROM VEGETATIVE CELLS OF DICTYOSTELIUM-DISCOIDEUM AND IDENTIFICATION

被引：45

作者：

KLEIN, R ^{[1
]}

THIERY, R ^{[1
]}

TATISCHEFF, I ^{[1
]}

机构：

[1] UNIV PARIS 06,F-75230 PARIS 05,FRANCE

来源：

EUROPEAN JOURNAL OF BIOCHEMISTRY | 1990年 / 187卷 / 03期

关键词：

D O I：

10.1111/j.1432-1033.1990.tb15351.x

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

A major pterin was isolated by reverse‐phase high‐performance liquid chromatography from cellular extract of vegetative cells of Dictyostelium discoideum after perchloric deproteinization and oxidation with acidic iodine. This compound was characterized by its chromatographic behavior, its absorption and fluorescence properties, by its oxidation product with alkaline permanganate, by secondary ion mass spectrometry and by circular dichroism. The final identification was obtained by comparison with authentic materials. It is concluded that the major pterin of D. discoideum is the compound 6‐(D‐threo‐1,2‐dihydroxypropyl)‐pterin. The name dictyopterin is proposed for this new natural isomer of L‐biopterin. Copyright © 1990, Wiley Blackwell. All rights reserved

引用

页码：665 / 669

页数：5

共 17 条

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