AMPEROMETRIC BIOSENSORS FOR GLUCOSE BASED ON CARBON PASTE MODIFIED ELECTRODES

被引：70

作者：

AMINE, A ^{[1
]}

KAUFFMANN, JM ^{[1
]}

PATRIARCHE, GJ ^{[1
]}

机构：

[1] UNIV LIBRE BRUXELLES,INST PHARM,CAMPUS PLAINE,CP 205-6,BD TRIOMPHE,B-1050 BRUSSELS,BELGIUM

来源：

TALANTA | 1991年 / 38卷 / 01期

关键词：

D O I：

10.1016/0039-9140(91)80016-S

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The modification of carbon-paste electrodes by incorporation of the enzyme glucose oxidase (GOD) is described. The resulting probes can be operated as amperometric glucose sensors in the presence or absence of a mediator (1,1'-dimethylferrocene) mixed into the paste. Extended linear calibration ranges have been obtained up to 90 and 50mM glucose respectively. The electrode responses were rapid, reaching steady-state values within 30-40 sec. Advantages of using a GOD-paste formulation are suggested. Plasma glucose assays were correlated with spectrophotometric determinations based on glucose oxidase (y = 1.07x -0.16, r = 0.973, n = 17).

引用

页码：107 / 110

页数：4

共 23 条

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