HYPOTENSIVE EFFECT AND ENZYME-INHIBITION ACTIVITY OF MAPUCHE MEDICINAL PLANT-EXTRACTS

被引：36

作者：

SCHMEDAHIRSCHMANN, G

LOYOLA, JI

SIERRA, J

RETAMAL, R

RODRIGUEZ, J

机构：

[1] Departamento de Biologia, Universidad de Talca, Talca, 747, Casilla

来源：

PHYTOTHERAPY RESEARCH | 1992年 / 6卷 / 04期

关键词：

MEDICINAL PLANTS; MAPUCHE; HYPOTENSIVE EFFECT; XANTHINE OXIDASE; BETA-GLUCURONIDASE; ENZYME INHIBITION; BRINE SHRIMP TOXICITY; BIOLOGICAL ACTIVITIES;

D O I：

10.1002/ptr.2650060404

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

Thirty-five plant samples belonging to 30 Mapuche medicinal plants were assayed for xanthine oxidase and beta-glucuronidase inhibitory activity as weil as for brine shrimp toxicity and hypotensive effect in normotensive rats. A high number of extracts displayed significant inhibition towards the enzyme-beta-glucuronidase or elicited a hypotensive response. The biological activity of the assayed extracts shows some correlation with their use as digestives for treating hepatic troubles by the Mapuche Amerindians. From the ten plants displaying a hypotensive effect greater-than-or-equal-to 20%, eight have some ethnobotanical indication suggesting that activity.

引用

页码：184 / 188

页数：5

共 13 条

[1] SPECIFIC-INHIBITION OF HUMAN BETA-D-GLUCURONIDASE AND ALPHA-L-IDURONIDASE BY A TRIHYDROXY PIPECOLIC ACID OF PLANT-ORIGIN [J].