The Pharmacology of Acute Lung Injury in Sepsis

被引:50
作者
Varisco, Brian Michael [1 ]
机构
[1] Cincinnati Childrens Hosp Med Ctr, Div Crit Care, MLC 2005, Cincinnati, OH 45229 USA
关键词
D O I
10.1155/2011/254619
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Acute lung injury (ALI) secondary to sepsis is one of the leading causes of death in sepsis. As such, many pharmacologic and nonpharmacologic strategies have been employed to attenuate its course. Very few of these strategies have proven beneficial. In this paper, we discuss the epidemiology and pathophysiology of ALI, commonly employed pharmacologic and nonpharmacologic treatments, and innovative therapeutic modalities that will likely be the focus of future trials.
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页数:7
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