A case of sarcoidosis accompanying squamous cell carcinoma in the mandibular gingiva

被引：4

作者：

Hanibuchi, Masaki ^{[1
]}

Matsumori, Yuka ^{[1
]}

Nishioka, Yasuhiko ^{[1
]}

Sone, Saburo ^{[1
]}

机构：

[1] Univ Tokushima, Grad Sch, Inst Hlth Biosci, Dept Internal Med & Mol Therapeut, Tokushima, Japan

来源：

JOURNAL OF MEDICAL INVESTIGATION | 2005年 / 52卷 / 1-2期

关键词：

sarcoidosis; gingival cancer; chest high resolution CT;

D O I：

10.2152/jmi.52.118

中图分类号：

R-3 [医学研究方法]; R3 [基础医学];

学科分类号：

1001 ;

摘要：

A 51-year-old man with a history of gingival cancer two years previously was referred to our hospital for further examination of chest abnormal shadow. Bilateral hilar and mediastinal lymphadenopathy, diffuse small nodular opacities and pleural nodules were observed in chest high resolutionCT. Serum angiotensin converting enzyme and lysozyme were elevated. Transbronchial lung biopsy specimens demonstrated non-caseous granuloma. CD4-positive lymphocytes were increased in broncho-alveolar lavage (CD4/CD8 ratio 5.47). The patient was diagnosed as having sarcoidosis. Radiological findings were improved and serum angiotensin converting enzyme level was decreased to within the normal range by corticosteroid therapy (prednisolone 30 mg/day). This is the first report of sarcoidosis accompanying the gingival cancer.

引用

页码：118 / 121

页数：4

共 12 条

[1]

Brinker H., Wilbek E., The incidence of malignant tumors in patients with pulmonary sarcoidosis, Br J Cancer, 29, pp. 247-251, (1974)

[2]

Yamaguchi M., Odaka M., Hosoda Y., Iwai K., Tachibana T., Excess death of lung cancer among sarcoidosis patients, Sarcoidosis, 8, pp. 51-55, (1991)

[3]

Seersholm N., Vestbo J., Viskum K., Risk of malignant neoplasms in patients with pulmonary sarcoidosis, Thorax, 52, pp. 892-894, (1997)

[4]

Romer F.K., Hommelgaard P., Schou G., Sarcoidosis and cancer revisited: A long-term follow-up study of 555 Danish sarcoidosis patients, Eur Respir J, 12, pp. 906-912, (1998)

[5]

Pollock J.L., Catalane E., Metastatic ductal carcinoma of the parotid gland in a patient with sarcoidosis, Arch Dermatol, 115, pp. 1098-1099, (1979)

[6]

Sakula A., Bronchial carcinoma and sarcoidosis, Br J Cancer, 17, pp. 206-212, (1963)

[7]

Brinker H., Sarcoid reactions in malignant tumors, Cancer Treat Rev, 13, pp. 147-156, (1986)

[8]

Segawa Y., Takigawa N., Okahara M., Maeda Y., Takata I., Fujii M., Mogami H., Mandai K., Kataoka M., Primary lung cancer associated with diffuse granulomatous lesions in the pulmonary parenchyma, Intern Med, 35, pp. 728-731, (1996)

[9]

Osaki T., Yoneda K., Yamamoto T., Kimura T., Matuoka H., Sakai H., Ryoke K., Clinical investigation on pulmonary metastasis of head and neck carcinomas, Oncology, 59, pp. 196-203, (2000)

[10]

Yamasawa H., Ishii Y., Kitamura S., Concurrence of sarcoidosis and lung cancer. A report of four cases, Respiration, 67, pp. 90-93, (2000)

← 1 2 →