RANDOM ENERGY-MODEL FOR THE KINETICS OF RNA FOLDING

被引:14
作者
FERNANDEZ, A [1 ]
机构
[1] MED SCH MIAMI,DEPT BIOCHEM & MOLEC BIOL,MIAMI,FL 33101
关键词
9;
D O I
10.1103/PhysRevLett.65.2259
中图分类号
O4 [物理学];
学科分类号
0702 ;
摘要
Relaxation dynamics of metastable RNS folding are modeled by means of a master equation for the distribution of folded-state occupancies. The underlying primary sequence is considered to be random and uncorrelated. The model is tested vis-a'-vis a Monte Carlo simulation of kinetically governed refolding events. The validity of a random energy model is established. © 1990 The American Physical Society.
引用
收藏
页码:2259 / 2261
页数:3
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