A NEW ENZYMATIC-SYNTHESIS OF (R)-GAMMA-CHLORO-BETA-HYDROXYBUTYRONITRILE

被引：32

作者：

NAKAMURA, T

NAGASAWA, T

YU, FJ

WATANABE, I

YAMADA, H

机构：

[1] NAGOYA UNIV,DEPT APPL BIOL SCI,CHIKUSA KU,NAGOYA,AICHI 464,JAPAN

[2] KYOTO UNIV,DEPT AGR CHEM,SAKYO KU,KYOTO 606,JAPAN

来源：

TETRAHEDRON | 1994年 / 50卷 / 41期

关键词：

D O I：

10.1016/S0040-4020(01)89297-8

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A new enzymatic synthesis of (R)-gamma-chloro-beta-hydroxybutyronitrile from epichlorohydrin or 1,3-dichloro-2-propanol using halohydrin hydrogen-halide-lyase purified from a recombinant Escherichia coli that carried the enzyme gene of Corynebacterium sp. strain N-1074 was described.

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收藏

页码：11821 / 11826

页数：6

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