KADSULIGNANS-L-N, 3 DIBENZOCYCLOOCTADIENE LIGNANS FROM KADSURA-COCCINEA

被引：65

作者：

LIU, JS ^{[1
]}

LI, L ^{[1
]}

机构：

[1] ACAD SINICA,SHANGHAI INST MAT MED,SHANGHAI 200031,PEOPLES R CHINA

来源：

PHYTOCHEMISTRY | 1995年 / 38卷 / 01期

基金：

中国国家自然科学基金;

关键词：

KADSURA COCCINEA; SCHISANDRACEAE; LIGNANS; KADSULIGNANS L-N; NEOKADSURANIN; ATROPISOMERIZATION; ANTI-HIV;

D O I：

10.1016/0031-9422(94)00557-A

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Three new lignans, kadsulignans L-N, were isolated from the seeds of Kadsura coccinea, of which kadsulignan M shows anti-HIV activity in vitro. Their structures, including absolute configurations, were elucidated by spectroscopic analysis and chemical conversions. In addition, their atropisomerization and CD rule for assignment of biphenyl configuration were also discussed and the biphenyl configuration of neokadsuranin was revised as R.

引用

页码：241 / 245

页数：5

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