PROSPECTS FOR SPECIFIC IMMUNOTHERAPY IN MYASTHENIA-GRAVIS

被引：37

作者：

STEINMAN, L ^{[1
]}

MANTEGAZZA, R ^{[1
]}

机构：

[1] STANFORD UNIV, MED CTR, SCH MED, DEPT NEUROL & NEUROL SCI, STANFORD, CA 94305 USA

来源：

FASEB JOURNAL | 1990年 / 4卷 / 10期

关键词：

antibodies; autoimmune response; immunotherapy; myasthenia gravis; T cell tolerance;

D O I：

10.1096/fasebj.4.10.2197152

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Myasthenia gravis is an autoimmune disease resulting from a breakdown in T and B cell tolerance to acetylcholine receptor (AChR). Autoantibodies to AChR mediate the disease. Recent advances in experimental immunotherapy of autoimmune disease provide several possibilities for specific intervention in this well-characterized condition.

引用

页码：2726 / 2731

页数：6

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