ENZYMATIC RESOLUTIONS OF ALPHA-HYDROXYPROPIONIC AND BETA-HYDROXYPROPIONIC ACID-ESTERS

被引:7
作者
GRUBERKHADJAWI, M [1 ]
HONIG, H [1 ]
WEBER, H [1 ]
机构
[1] GRAZ UNIV TECHNOL,INST ORGAN CHEM,STREMAYRGASSE 16,A-8010 GRAZ,AUSTRIA
关键词
DIHYDROCINNAMIC ACID DERIVATIVES; HYDROXY AZIDO ACIDS; HYDROXY AMINO ACIDS; ENANTIOSELECTIVE HYDROLYSIS; PSEUDOMONAS-FL LIPASE; CANDIDA-CYCLINDRACEA LIPASE;
D O I
10.1002/chir.530040207
中图分类号
R914 [药物化学];
学科分类号
100701 ;
摘要
The synthesis of some acyloxy-methoxy-cinnamic acid derivatives, azidohydroxy butanoates, and azidohydroxy butanedioates in enantiomerically pure form is presented. Racemic diastereomerically pure educts were prepared in few steps. These racemates are resolved with lipases from Candida cylindracea (CC) and Pseudomonas fluorescens (P).
引用
收藏
页码:103 / 109
页数:7
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