THE LOW REACTIVITY OF 5H-DIBENZO[A,D]CYCLOHEPTENE 10,11-OXIDE IN MICROSOMAL EPOXIDE HYDROLASE CATALYZED HYDRATION

被引：5

作者：

BELLUCCI, G

CHIAPPE, C

MARIONI, F

SIMONELLI, C

机构：

来源：

XENOBIOTICA | 1989年 / 19卷 / 03期

关键词：

D O I：

10.3109/00498258909042273

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

收藏

页码：279 / 285

页数：7

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共 23 条

[1] BALSAMO A, 1976, GAZZ CHIM ITAL, V106, P77
[2] RESTRICTED CONFORMATIONAL PROCESSES IN 10,11-DIHYDRO-5H-DIBENZ[B,F]AZEPINE DERIVATIVES - A DNMR STUDY
BELLUCCI, G
BIANCHINI, R
CHIAPPE, C
MARIONI, F
CATALANO, D
[J]. TETRAHEDRON, 1988, 44 (15) : 4863 - 4870
[3] THE EPOXIDE HYDROLASE CATALYZED-HYDROLYSIS OF TRANS-3-BROMO-1,2-EPOXYCYCLOHEXANE - A DIRECT PROOF FOR A GENERAL BASE-CATALYZED MECHANISM OF THE ENZYMATIC HYDRATION
BELLUCCI, G
BERTI, G
FERRETTI, M
MARIONI, F
RE, F
[J]. BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1981, 102 (03) : 838 - 844
[4] THE METABOLISM OF CARBAMAZEPINE IN HUMANS - STERIC COURSE OF THE ENZYMATIC-HYDROLYSIS OF THE 10,11-EPOXIDE
BELLUCCI, G
BERTI, G
CHIAPPE, C
LIPPI, A
MARIONI, F
[J]. JOURNAL OF MEDICINAL CHEMISTRY, 1987, 30 (05) : 768 - 773
[5] REVERSIBILITY OF BROMONIUM ION FORMATION AND ITS EFFECT ON OLEFIN REACTIVITY IN ELECTROPHILIC BROMINATION - NEW EVIDENCE FROM THE 5H-DIBENZ[B,F]AZEPINE SYSTEM
BELLUCCI, G
BIANCHINI, R
CHIAPPE, C
MARIONI, F
SPAGNA, R
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1988, 110 (02) : 546 - 552
[6] BELLUCCI G, 1987, 17 CONV NAZ DIV CHIM, P110
[7] IDENTIFICATION OF CYCLOBENZAPRINE-10,11-EPOXIDE AND OTHER METABOLITES AFTER INCUBATION OF CYCLOBENZAPRINE WITH RAT-LIVER MICROSOMES
BELVEDERE, G
ROVEI, V
PANTAROTTO, C
FRIGERIO, A
[J]. XENOBIOTICA, 1975, 5 (12) : 765 - 771
[8] SYNTHESE DES 2'-ACETAMINO-2,3 - 6,7-DIBENZO-TROPILIDENS UND DES 2-ACETAMINO-9,9-DIMETHYL-FLUORENS
CAMPBELL, TW
GINSIG, R
SCHMID, H
[J]. HELVETICA CHIMICA ACTA, 1953, 36 (06) : 1489 - 1499
[9] MECHANISM OF CATALYSIS FOR HYDRATION OF SUBSTITUTED STYRENE OXIDES BY HEPATIC EPOXIDE HYDRASE
DANSETTE, PM
MAKEDONSKA, VB
JERINA, DM
[J]. ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1978, 187 (02) : 290 - 298
[10] DUBOIS GC, 1978, J BIOL CHEM, V253, P2932