CYTOGENETIC EFFECTS OF DIAZEPAM IN PERIPHERAL LYMPHOCYTES OF SELF-POISONED PERSONS

被引：9

作者：

VANBAO, T ^{[1
]}

IMREH, E ^{[1
]}

CZEIZEL, AE ^{[1
]}

机构：

[1] NATL INST HYG,WHO,COLLABORATING CTR COMMUNITY CONTROL HEREDITARY DIS,BUDAPEST,HUNGARY

来源：

MUTATION RESEARCH | 1992年 / 298卷 / 02期

关键词：

CHROMOSOME ABERRATIONS; MICRONUCLEI; DIAZEPAM INTOXICATION;

D O I：

10.1016/0165-1218(92)90038-2

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The frequencies of chromosomal aberrations and of micronuclei were determined in lymphocyte cultures of 25 patients who attempted suicide with diazepam, 6-12 h, 72 h and 30 days after self-poisoning. These data were compared with those of healthy controls. The frequencies of numerical aberrations showed a significant increase immediately after self-poisoning. However, this effect could not be detected on the 3rd and 30th days after self-poisoning.

引用

页码：131 / 137

页数：7

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