STEREOSELECTIVITIES IN THE COUPLING REACTION BETWEEN SILYLATED PYRIMIDINE-BASES AND 1-HALO-2,3-DIDEOXYRIBOSE

被引：34

作者：

KAWAKAMI, H ^{[1
]}

EBATA, T ^{[1
]}

KOSEKI, K ^{[1
]}

MATSUMOTO, K ^{[1
]}

MATSUSHITA, H ^{[1
]}

NAOI, Y ^{[1
]}

ITOH, K ^{[1
]}

机构：

[1] YUKI GOSEI KOGYO LTD,TOKYO RES LAB,ITABASHI KU,TOKYO 174,JAPAN

来源：

HETEROCYCLES | 1990年 / 31卷 / 11期

关键词：

D O I：

10.3987/COM-90-5563

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Coupling reactions between 1-chloro-2,3-dideoxyribose and silylated pyrimidines have been examined from the point of stereoselectivity. When the reaction was carried out in chloroform, the selectivity was in the anomeric ratio of alpha:beta = 4:6. On the other hand, the presence of tertiary amine raises the selectivity to alpha:beta = 3:7.

引用

页码：2041 / 2054

页数：14

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