A MULTIPLE-DOSE PHASE-I TRIAL OF RECOMBINANT LEUKOCYTE-A INTERFERON IN CANCER-PATIENTS

被引：170

作者：

SHERWIN, SA ^{[1
]}

KNOST, JA ^{[1
]}

FEIN, S ^{[1
]}

ABRAMS, PG ^{[1
]}

FOON, KA ^{[1
]}

OCHS, JJ ^{[1
]}

SCHOENBERGER, C ^{[1
]}

MALUISH, AE ^{[1
]}

OLDHAM, RK ^{[1
]}

机构：

[1] HOFFMANN LA ROCHE INC,NUTLEY,NJ 07110

来源：

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION | 1982年 / 248卷 / 19期

关键词：

D O I：

10.1001/jama.248.19.2461

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

引用

页码：2461 / 2466

页数：6

共 20 条

[1] INTERFERONS - RATIONALE FOR CLINICAL-TRIALS IN NEOPLASTIC DISEASE
BORDEN, EC
[J]. ANNALS OF INTERNAL MEDICINE, 1979, 91 (03) : 472 - 479
[2] INTERFERON AND SPONTANEOUS CYTOTOXICITY IN MAN .1. ENHANCEMENT OF SPONTANEOUS CYTOTOXICITY OF PERIPHERAL LYMPHOCYTES BY HUMAN LEUKOCYTE INTERFERON
EINHORN, S
BLOMGREN, H
STRANDER, H
[J]. INTERNATIONAL JOURNAL OF CANCER, 1978, 22 (04) : 405 - 412
[3] HUMAN-LEUKOCYTE INTERFERON PRODUCED BY ESCHERICHIA-COLI IS BIOLOGICALLY-ACTIVE
GOEDDEL, DV
YELVERTON, E
ULLRICH, A
HEYNEKER, HL
MIOZZARI, G
HOLMES, W
SEEBURG, PH
DULL, T
MAY, L
STEBBING, N
CREA, R
MAEDA, S
MCCANDLISS, R
SLOMA, A
TABOR, JM
GROSS, M
FAMILLETTI, PC
PESTKA, S
[J]. NATURE, 1980, 287 (5781) : 411 - 416
[4] LEUKOCYTE INTERFERON-INDUCED TUMOR-REGRESSION IN HUMAN METASTATIC BREAST-CANCER, MULTIPLE-MYELOMA, AND MALIGNANT-LYMPHOMA
GUTTERMAN, JU
BLUMENSCHEIN, GR
ALEXANIAN, R
YAP, HY
BUZDAR, AU
CABANILLAS, F
HORTOBAGYI, GN
HERSH, EM
RASMUSSEN, SL
HARMON, M
KRAMER, M
PESTKA, S
[J]. ANNALS OF INTERNAL MEDICINE, 1980, 93 (03) : 399 - 406
[5] RECOMBINANT LEUKOCYTE-A INTERFERON - PHARMACOKINETICS, SINGLE-DOSE TOLERANCE, AND BIOLOGIC EFFECTS IN CANCER-PATIENTS
GUTTERMAN, JU
FINE, S
QUESADA, J
HORNING, SJ
LEVINE, JF
ALEXANIAN, R
BERNHARDT, L
KRAMER, M
SPIEGEL, H
COLBURN, W
TROWN, P
MERIGAN, T
DZIEWANOWSKI, Z
[J]. ANNALS OF INTERNAL MEDICINE, 1982, 96 (05) : 549 - 556
[6] EFFECT OF HUMAN RECOMBINANT INTERFERON ON CYTO-TOXIC ACTIVITY OF NATURAL-KILLER (NK) CELLS AND MONOCYTES
HERBERMAN, RB
ORTALDO, JR
MANTOVANI, A
HOBBS, DS
KUNG, HF
PESTKA, S
[J]. CELLULAR IMMUNOLOGY, 1982, 67 (01) : 160 - 167
[7] AUGMENTATION BY INTERFERON OF HUMAN NATURAL AND ANTIBODY-DEPENDENT CELL-MEDIATED CYTOTOXICITY
HERBERMAN, RR
ORTALDO, JR
BONNARD, GD
[J]. NATURE, 1979, 277 (5693) : 221 - 223
[8] HILL N O, 1979, Journal of Clinical Hematology and Oncology, V9, P137
[9] CLINICAL AND IMMUNOLOGICAL EFFECTS OF RECOMBINANT LEUKOCYTE A INTERFERON IN 8 PATIENTS WITH ADVANCED CANCER
HORNING, SJ
LEVINE, JF
MILLER, RA
ROSENBERG, SA
MERIGAN, TC
[J]. JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION, 1982, 247 (12): : 1718 - 1722
[10] VIRUS INTERFERENCE .1. THE INTERFERON
ISAACS, A
LINDENMANN, J
[J]. PROCEEDINGS OF THE ROYAL SOCIETY SERIES B-BIOLOGICAL SCIENCES, 1957, 147 (927): : 258 - 267

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