TRANSPLANTATION OF SEROTONERGIC NEURONS INTO THE 5,7-DHT-LESIONED RAT OLFACTORY-BULB RESTORES THE PARAMETERS OF KINDLING

被引：14

作者：

CAMU, W

MARLIER, L

LERNERNATOLI, M

RONDOUIN, G

PRIVAT, A

机构：

[1] INST BIOL,NEUROBIOL DEV LAB,CNRS,UPR 8402,INSERM,U249,F-34060 MONTPELLIER,FRANCE

[2] INST BIOL,MED EXPTL LAB,CNRS,UPR 8402,INSERM,U249,F-34060 MONTPELLIER,FRANCE

来源：

BRAIN RESEARCH | 1990年 / 518卷 / 1-2期

关键词：

5,7-Dihydroxytryptamine; Kindling; Olfactory bulb; Serotonergic neuron; Transplantation;

D O I：

10.1016/0006-8993(90)90949-C

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

In order to restore a normal pattern of kindling, kindled rats, previously lesioned in the olfactory nuclei with 5,7-dihydroxytryptamine, were grafted with serotonin (5-HT) neurons in the right olfactory bulb and then implanted for kindling procedure. It was observed that complete 5-HT lesions accelerated the kindling profile, and that the transplants containing 5-HT neurons restored, in lesioned rats, quite normal parameters. © 1990.

引用

页码：23 / 30

页数：8

共 27 条

[1] GRAFTED NORADRENERGIC NEURONS SUPPRESS SEIZURE DEVELOPMENT IN KINDLING-INDUCED EPILEPSY [J].