A NEW FIBRIN SEAL IN PRIMARY REPAIR OF PERIPHERAL-NERVES

被引：19

作者：

POVLSEN, B

机构：

[1] Deparment of Hand and Plastic Surgery, University Hospital of Linköping, University of Linköping

[2] Department of Cell Biology, University of Linköping

来源：

JOURNAL OF HAND SURGERY-BRITISH AND EUROPEAN VOLUME | 1994年 / 19B卷 / 01期

关键词：

D O I：

10.1016/0266-7681(94)90048-5

中图分类号：

R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学（修复外科学）];

学科分类号：

摘要：

Fibrin sealing, with or without sutures, has become a commonly used technique in human nerve grafting with clinically good results, but is seldom used in primary repair of peripheral nerves. A prospective study was designed to evaluate the incidence of dehiscence in the traditional (Tisseel Kit) and a new ''ready-to-use'' fibrin seal preparation (Tisseel Due), and the outcome following fibrin sealing was compared with microsurgical repair of peripheral nerves in rats. No dehiscence was seen in the Tisseel Duo group compared with 20% in the Tisseel Kit group. The electron micrographic evaluation following regeneration showed no significant difference from the microsuture group. Tisseel Duo should therefore be used instead of the traditional fibrin seal preparation when no sutures are used, and may prove to be an alternative to microsuture of peripheral nerves.

引用

页码：43 / 47

页数：5

共 18 条

[1]

Berthold, A study on the fixation of large mature feline myelinated ventral lumbar spinal-root fibres, Acta Societatis Medicorum Upsaliensis, 73, pp. 1-36, (1968)

[2]

Bento, Miniti, Comparison between fibrin tissue adhesive, epineural suture and natural union in intratemporal facial nerve of cats, Acta Oto-laryngologica, 105, pp. 4-35, (1989)

[3]

Cruz, Debs, Fiol, Evaluation of fibrin glue in rat sciatic nerve repairs, Plastic and Reconstructive Surgery, 78, 3, pp. 369-373, (1986)

[4]

Ejlertsson, Grundläggande Statistik., pp. 138-141, (1984)

[5]

Gelberman, Operative Nerve Repair and Reconstruction, (1992)

[6]

Haase, Andreasen, Falk, Madsen, Teglbjarg, Use of fibrin seal (Tisseel/Tissucol) in peripheral nerve surgery: An experimental rat model, Opthalmology-Neurosurgery, 2, pp. 196-197, (1986)

[7]

Herter, Problems of fibrin adhesion of the nerves, Neurosurgery Review, 11, pp. 249-258, (1988)

[8]

Hildebrand, Povlsen, Cutaneous, muscular and articular nerve fibre regeneration after rat sciatic nerve lesions, Society of Neuroscience Abstracts, 17, (1991)

[9]

Jenq, Coggeshall, Regeneration of axons in tributary nerves, Brain Research, 310, pp. 107-121, (1984)

[10]

Karnes, Robb, O'Brien, Lambert, Dyck, Computerized image recognition for morphometry of nerve attribute of shape of sampled transverse sections of myelinated fibers which best estimates their average diameter, Journal of the Neurological Sciences, 34, pp. 43-51, (1977)

← 1 2 →