EFFECTS OF ALKALINITY ON THE EYE IRRITATION POTENTIAL OF SOLUTIONS PREPARED AT A SINGLE PH

被引:6
作者
NEUN, DJ
机构
[1] The Soap and Detergent Association, NY
来源
JOURNAL OF TOXICOLOGY-CUTANEOUS AND OCULAR TOXICOLOGY | 1993年 / 12卷 / 03期
关键词
D O I
10.3109/15569529309053635
中图分类号
R77 [眼科学];
学科分类号
100212 ;
摘要
To determine the effects of solution alkalinity on eye irritation, a modified Draize eye irritancy test was performed using 3 differently buffered solutions, at specified alkalinities, set at a pH of 11.5. The maximum average Draize score and median days to clear indicated that solutions with a low buffering capacity are not necessarily irritants at a pH considered to indicate high eye irritation potential.
引用
收藏
页码:227 / 231
页数:5
相关论文
共 9 条
[1]  
BOOMAN KA, 1988, J TOXICOL-CUTAN OCUL, V7, P173
[2]  
BOOMAN KA, 1989, J TOXICOL-CUTAN OCUL, V8, P35
[3]  
DRAIZE JH, 1975, APPRAISAL SAFETY CHE, P49
[4]  
Kay J.H., 1962, J SOC COSMET CHEM, V13, P281
[5]  
1987, ORG EC COOPERATION D, V402
[6]  
1985, FED REG, V40
[7]  
1990, EEC79831 EUR EC COMM
[8]  
1987, ORG EC COOPERATION D, V405
[9]  
1987, ORG EC COOPERATION D, V404