NEW CHIRAL RECOGNITION ABILITY OF A STEROIDAL BILE-ACID - DIRECT EVIDENCE FOR EFFICIENT OPTICAL RESOLUTION OF RACEMIC LACTONES BY CHOLIC-ACID INCLUSION CRYSTALS

被引：59

作者：

MIKI, K

KASAI, N

SHIBAKAMI, M

TAKEMOTO, K

MIYATA, M

机构：

[1] OSAKA UNIV,FAC ENGN,DEPT APPL CHEM,SUITA,OSAKA 565,JAPAN

[2] OSAKA UNIV,FAC ENGN,DEPT APPL FINE CHEM,SUITA,OSAKA 565,JAPAN

[3] GIFU UNIV,FAC ENGN,DEPT APPL CHEM,GIFU 50111,JAPAN

来源：

JOURNAL OF THE CHEMICAL SOCIETY-CHEMICAL COMMUNICATIONS | 1991年 / 24期

关键词：

D O I：

10.1039/c39910001757

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

A new chiral recognition ability has been found for cholic acid inclusion crystals, in which only one enantiomer of a guest lactone can be accommodated in the channels of the host steroidal molecules by crystallization from racemic solution; direct evidence for this phenomenon was obtained from the crystal structure of the 1:1 inclusion compound between cholic acid and gamma-valerolactone.

引用

页码：1757 / 1759

页数：3

共 21 条

[11]

Lessinger L, 1982, CRYST STRUCT COMMUN, V11, P1787

[12] CRYSTAL-STRUCTURE OF CHOLIC-ACID WITH NO GUEST MOLECULES [J].