PROTEASES AND LYMPHOCYTE CYTOTOXIC KILLING MECHANISMS

被引：73

作者：

HUDIG, D ^{[1
]}

EWOLDT, GR ^{[1
]}

WOODARD, SL ^{[1
]}

机构：

[1] UNIV NEVADA, COLL AGR, RENO, NV 89557 USA

来源：

CURRENT OPINION IN IMMUNOLOGY | 1993年 / 5卷 / 01期

关键词：

D O I：

10.1016/0952-7915(93)90086-8

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A subfamily of serine proteases is uniquely expressed by cytotoxic natural killer lymphocytes and T cells. Protease cleavage of different natural substrates is now implicated in the cytotoxic mechanisms of target cell membrane pore formation, DNA fragmentation and cytostasis.

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收藏

页码：90 / 96

页数：7

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