NEW SPONGIAN DITERPENOIDS FROM A GREAT-BARRIER-REEF SPONGE, SPONGIA SP

被引：41

作者：

GUNASEKERA, SP ^{[1
]}

SCHMITZ, FJ ^{[1
]}

机构：

[1] UNIV OKLAHOMA,DEPT CHEM & BIOCHEM,NORMAN,OK 73019

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1991年 / 56卷 / 03期

关键词：

D O I：

10.1021/jo00003a057

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Four new spongian diterpenes, 4-6 and 8, have been isolated from a Spongia sp. of sponge collected on the Great Barrier Reef. Two of the diterpenes have ring-A lactones instead of the conventional cyclohexane rings. Structures were determined primarily by proton and carbon-13 NMR analyses. One of the metabolites is slightly cytotoxic to murine leukemia cells.

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页码：1250 / 1253

页数：4

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