RETENTION BEHAVIOR OF SOME MONOBASIC PENICILLINS AND THEIR QUATERNARY AMMONIUM ION-PAIRS IN REVERSED-PHASE HIGH-PERFORMANCE LIQUID-CHROMATOGRAPHY

被引：7

作者：

FLETOURIS, DJ ^{[1
]}

PSOMAS, JE ^{[1
]}

MANTIS, AJ ^{[1
]}

机构：

[1] ARISTOTELIAN UNIV SALONIKA,SCH VET MED,FOOD HYG LAB,GR-54006 SALONIKA,GREECE

来源：

CHROMATOGRAPHIA | 1991年 / 32卷 / 9-10期

关键词：

COLUMN LIQUID CHROMATOGRAPHY; ION-PAIR CHROMATOGRAPHY; QUATERNARY AMMONIUM ION PAIRS; PENICILLINS; RETENTION BEHAVIOR;

D O I：

10.1007/BF02327974

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The retention behavior of some monobasic penicillins (penicillin G, penicillin V, oxacillin, cloxacillin and dicloxacillin) and their quaternary alkylammonium ion pairs has been studied in a reversed-phase high-performance liquid chromatographic system using Partisil 5-mu-m ODS-3 as stationary phase and mixtures of acetonitrile and aqueous phosphate buffers as mobile phases. The influence of pH, pairing-ion chain length and concentration, and column temperature on retention has been investigated and the observed behavior of the compounds during the chromatographic process has been discussed.

引用

页码：436 / 440

页数：5

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