ENALAPRIL INDUCED ANGIOEDEMA

被引：21

作者：

GIANOS, ME ^{[1
]}

KLAUSTERMEYER, WB ^{[1
]}

KUROHARA, M ^{[1
]}

TARNASKY, P ^{[1
]}

GORDON, E ^{[1
]}

机构：

[1] UNIV CALIF LOS ANGELES,VET ADM WADSWORTH MED CTR,SCH MED,DIV ALLERGY IMMUNOL W111R,LOS ANGELES,CA 90073

来源：

AMERICAN JOURNAL OF EMERGENCY MEDICINE | 1990年 / 8卷 / 02期

关键词：

angiodema; bradykinin; Enalapril;

D O I：

10.1016/0735-6757(90)90198-9

中图分类号：

R4 [临床医学];

学科分类号：

1002 ; 100602 ;

摘要：

A report of three patients who developed anglodema while receiving enalapril. Patient 1 came in with an 8-hour history of facial swelling after enalapril had been started 2 days earlier. The second patient came in with severe angiodema of the tongue, larynx, and glottls requiring emergency tracheostomy, hydroxyzine, and steroids. He had been treated with enalapril for 1 year. The third patient developed facial swelling within a few hours of the first dose of enalapril. Angiodema with enalapril can occur early or late in the course of therapy. A possible mechanism for this drug reaction is the potentiation of bradykinin with resultant kinin system activation. © 1990.

引用

页码：124 / 126

页数：3

共 11 条

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