INCREASED ALKYLATION OF LIVER DNA AND CELL TURNOVER IN YOUNG VERSUS OLD RATS EXPOSED TO VINYL-CHLORIDE CORRELATES WITH CANCER SUSCEPTIBILITY

被引：13

作者：

LAIB, RJ ^{[1
]}

BOLT, HM ^{[1
]}

CARTIER, R ^{[1
]}

BARTSCH, H ^{[1
]}

机构：

[1] INT AGCY RES CANC,F-69372 LYON 08,FRANCE

来源：

TOXICOLOGY LETTERS | 1989年 / 45卷 / 2-3期

关键词：

D O I：

10.1016/0378-4274(89)90014-3

中图分类号：

R99 [毒物学（毒理学）];

学科分类号：

100405 ;

摘要：

引用

页码：231 / 239

页数：9

共 13 条

[1]

BOLT HM, 1982, FRONTIERS LIVER DISE, P80

[2]

EBERLE G, 1988, IN PRESS CARCINOGENE

[3] INTERACTIONS OF VINYL-CHLORIDE WITH RAT-LIVER DNA INVIVO [J].

GREEN, T ;

HATHWAY, DE .

CHEMICO-BIOLOGICAL INTERACTIONS, 1978, 22 (2-3) :211-224

[4]

Laib R J, 1986, IARC Sci Publ, P101

[5] THE RAT-LIVER FOCI BIOASSAY .2. INVESTIGATIONS ON THE DOSE-DEPENDENT INDUCTION OF ATPASE-DEFICIENT FOCI BY VINYL-CHLORIDE AT VERY LOW-DOSES [J].

LAIB, RJ ;

PELLIO, T ;

WUNSCHEL, UM ;

ZIMMERMANN, N ;

BOLT, HM .

CARCINOGENESIS, 1985, 6 (01) :69-72

[6] THE RAT-LIVER FOCI BIOASSAY .1. AGE-DEPENDENCE OF INDUCTION BY VINYL-CHLORIDE OF ATPASE-DEFICIENT FOCI [J].

LAIB, RJ ;

KLEIN, KP ;

BOLT, HM .

CARCINOGENESIS, 1985, 6 (01) :65-68

[7] ALKYLATION OF RNA BY VINYL-CHLORIDE METABOLITES INVITRO AND INVIVO - FORMATION OF 1-N6-ETHENO-ADENOSINE [J].

LAIB, RJ ;

BOLT, HM .

TOXICOLOGY, 1977, 8 (02) :185-195

[8] DNA ALKYLATION BY VINYL-CHLORIDE METABOLITES - ETHENO DERIVATIVES OR 7-ALKYLATION OF GUANINE [J].

LAIB, RJ ;

GWINNER, LM ;

BOLT, HM .

CHEMICO-BIOLOGICAL INTERACTIONS, 1981, 37 (1-2) :219-231

[9] CARCINOGENICITY BIOASSAYS OF VINYL-CHLORIDE MONOMER - A MODEL OF RISK ASSESSMENT ON AN EXPERIMENTAL BASIS [J].

MALTONI, C ;

LEFEMINE, G ;

CILIBERTI, A ;

COTTI, G ;

CARRETTI, D .

ENVIRONMENTAL HEALTH PERSPECTIVES, 1981, 41 (OCT) :3-29

[10] ACCUMULATION OF O6-METHYLGUANINE IN NON-TARGET-TISSUE DEOXYRIBONUCLEIC-ACID DURING CHRONIC ADMINISTRATION OF DIMETHYLNITROSAMINE [J].

MARGISON, GP ;

MARGISON, JM ;

MONTESANO, R .

BIOCHEMICAL JOURNAL, 1977, 165 (03) :463-468

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